A 63 year old female was admitted for investigation of worsening renal insufficiency. During hospitalization she developed persistent immune thrombocytopenia refractory to supportive or immunosuppressive treatment. She was diagnosed with Mycobacterium chimaera prosthetic valve endocarditis and thrombocytopenia resolved with anti-mycobacterial therapy.
Keywords: ANA, anti-nuclear antibodies; ANCA, anti-neutrophil cytoplasmic antibodies; AVR, aortic valve repair; Aortic root abscess; CT, computerized tomography; ENA, extractable nuclear antigen; Granulomas; HIV, human immunodeficiency virus; ITP, immune thrombocytopenia purpura; IVIG, intravenous immunoglobulin; MRI, magnetic resonance imaging; Mycobacterium chimaera; PVE, prosthetic valve endocarditis; Prosthetic-valve endocarditis; TEE, transesophageal echocardiogram; Thrombocytopenia; eGFR, estimated glomerular filtration rate.