CRISPR-Cas9-mediated multiplex gene editing in CAR-T cells

Cell Res. 2017 Jan;27(1):154-157. doi: 10.1038/cr.2016.142. Epub 2016 Dec 2.

Xiaojuan Liu¹, Yongping Zhang², Chen Cheng^{1

3}, Albert W Cheng⁴, Xingying Zhang^{1

5}, Na Li¹, Changqing Xia^{2

6}, Xiaofei Wei⁷, Xiang Liu¹, Haoyi Wang^{1

5

8}

¹ State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, The Chinese Academy of Sciences, Beijing, China.
² Department of Hematology, Xuanwu Hospital, Capital Medical University, Beijing, China.
³ Graduate School, University of Science and Technology of China, Hefei, China.
⁴ The Jackson Laboratory for Genome Medicine, Farmington, CN, USA.
⁵ University of Chinese Academy of Sciences.
⁶ Department of Pathology, Immunology and Laboratory Medicine, University of Florida, FL, USA.
⁷ Beijing Cord Blood Bank, Beijing, China.
⁸ The Jackson Laboratory, Bar Harbor, ME, USA.

No abstract available

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