Enhancing Stem Cell Transplantation with "Nutri-technology"

Cell Stem Cell. 2016 Dec 1;19(6):681-682. doi: 10.1016/j.stem.2016.11.015.


It is necessary to employ myeloablative irradiation or chemotherapy to deplete the HSC niche to optimize hematopoietic stem cell transplantation. In a recent issue of Science, Taya and colleagues provide evidence for an alternative to the toxic chemoirradiative procedure by showing that a valine-restricted diet is sufficient to empty the bone marrow niche.

Publication types

  • Comment

MeSH terms

  • Bone Marrow
  • Bone Marrow Transplantation
  • Hematopoietic Stem Cell Transplantation
  • Hematopoietic Stem Cells*
  • Humans
  • Stem Cell Niche*