Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
, 5, 281-307

Deciphering the Origin of Dogs: From Fossils to Genomes


Deciphering the Origin of Dogs: From Fossils to Genomes

Adam H Freedman et al. Annu Rev Anim Biosci.


Understanding the timing and geographic context of dog origins is a crucial component for understanding human history, as well as the evolutionary context in which the morphological and behavioral divergence of dogs from wolves occurred. A substantial challenge to understanding domestication is that dogs have experienced a complicated demographic history. An initial severe bottleneck was associated with domestication followed by postdivergence gene flow between dogs and wolves, as well as population expansions, contractions, and replacements. In addition, because the domestication of dogs occurred in the relatively recent past, much of the observed polymorphism may be shared between dogs and wolves, limiting the power to distinguish between alternative models of dog history. Greater insight into the domestication process will require explicit tests of alternative models of domestication through the joint analysis of whole genomes from modern lineages and ancient wolves and dogs from across Eurasia.

Keywords: dog domestication; fossil record; genomics; human history; phylogeny.

Similar articles

  • Genome sequencing highlights the dynamic early history of dogs.
    Freedman AH, Gronau I, Schweizer RM, Ortega-Del Vecchyo D, Han E, Silva PM, Galaverni M, Fan Z, Marx P, Lorente-Galdos B, Beale H, Ramirez O, Hormozdiari F, Alkan C, Vilà C, Squire K, Geffen E, Kusak J, Boyko AR, Parker HG, Lee C, Tadigotla V, Wilton A, Siepel A, Bustamante CD, Harkins TT, Nelson SF, Ostrander EA, Marques-Bonet T, Wayne RK, Novembre J. Freedman AH, et al. PLoS Genet. 2014 Jan;10(1):e1004016. doi: 10.1371/journal.pgen.1004016. Epub 2014 Jan 16. PLoS Genet. 2014. PMID: 24453982 Free PMC article.
  • Estimation of population divergence times from non-overlapping genomic sequences: examples from dogs and wolves.
    Skoglund P, Götherström A, Jakobsson M. Skoglund P, et al. Mol Biol Evol. 2011 Apr;28(4):1505-17. doi: 10.1093/molbev/msq342. Epub 2010 Dec 21. Mol Biol Evol. 2011. PMID: 21177316
  • Complete mitochondrial genomes of ancient canids suggest a European origin of domestic dogs.
    Thalmann O, Shapiro B, Cui P, Schuenemann VJ, Sawyer SK, Greenfield DL, Germonpré MB, Sablin MV, López-Giráldez F, Domingo-Roura X, Napierala H, Uerpmann HP, Loponte DM, Acosta AA, Giemsch L, Schmitz RW, Worthington B, Buikstra JE, Druzhkova A, Graphodatsky AS, Ovodov ND, Wahlberg N, Freedman AH, Schweizer RM, Koepfli KP, Leonard JA, Meyer M, Krause J, Pääbo S, Green RE, Wayne RK. Thalmann O, et al. Science. 2013 Nov 15;342(6160):871-4. doi: 10.1126/science.1243650. Science. 2013. PMID: 24233726
  • Evolutionary genomics of dog domestication.
    Wayne RK, vonHoldt BM. Wayne RK, et al. Mamm Genome. 2012 Feb;23(1-2):3-18. doi: 10.1007/s00335-011-9386-7. Epub 2012 Jan 22. Mamm Genome. 2012. PMID: 22270221 Review.
  • Toward understanding dog evolutionary and domestication history.
    Galibert F, Quignon P, Hitte C, André C. Galibert F, et al. C R Biol. 2011 Mar;334(3):190-6. doi: 10.1016/j.crvi.2010.12.011. Epub 2011 Feb 1. C R Biol. 2011. PMID: 21377613 Review.
See all similar articles

Cited by 11 articles

See all "Cited by" articles

LinkOut - more resources