Psychological well-being and mental health recovery in the NIMH RAISE early treatment program

Schizophr Res. 2017 Jul;185:167-172. doi: 10.1016/j.schres.2016.11.032. Epub 2016 Nov 29.


Recovery-oriented practices that promote client-centered care, collaboration, and functional outcome have been recommended to improve treatment engagement, especially for individuals with serious mental illness (SMI). Psychological well-being (PWB) is related to recovery and refers to experiencing purpose and meaning in life through realizing one's potential. The recently completed Recovery After an Initial Schizophrenia Episode Early Treatment Program (RAISE ETP) study sought to improve quality of life, functional outcome, and well-being in individuals with first episode psychosis (FEP). Therefore, the primary aims of the present analysis were: 1) to examine the impact of treatment on PWB and mental health recovery trajectories, 2) to examine the impact of duration of untreated psychosis (DUP) on these outcomes, and 3) to examine the relationships among these outcomes and quality of life. Multilevel modeling was used given the nested data structure. Results revealed that PWB and mental health recovery improved over the course of the 2-year treatment; there were no significant treatment differences. In addition, DUP was associated with the Positive Relationships and Environmental Mastery dimensions of PWB. Finally, PWB, mental health recovery, and quality of life were all significantly correlated at baseline while controlling for depressive symptoms. Overall, the findings indicate that PWB and mental health recovery can improve in FEP, are related to yet distinct from quality of life, and that DUP may play a role in certain facets of these constructs.

Keywords: Coordinated specialty care; First episode psychosis; Psychological well-being.

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Early Intervention, Educational / methods*
  • Female
  • Humans
  • Male
  • Mental Health Recovery*
  • Outcome Assessment, Health Care
  • Psychiatric Status Rating Scales
  • Psychotic Disorders / psychology*
  • Psychotic Disorders / therapy*
  • Quality of Life
  • Retrospective Studies
  • Schizophrenia / diagnosis*
  • Schizophrenia / therapy
  • Schizophrenic Psychology*
  • Time Factors
  • Young Adult