Stimulation of Protein Expression Through the Harmonic Resonance of Frequency-Specific Music

Clin Invest Med. 2016 Dec 1;39(6):27498.


Purpose: The use of specific frequencies for specific individual amino acids may increase the potential energy of protein molecules in the medium [1]. The resonance would also increase the movement of particles in the cytosol, increasing the collisions necessary for the conduction of protein expression.

Methods: The clash of two waves that share frequencies will exhibit an increase in energy through an increase in amplitude [2]. The increase in energy would in turn increase the number of collisions forming the tRNA-amino acid, increasing the amino acid acquiry for ribosomes to improve intracellular efficiency in gene expression. To test the hypothesis, Red Fluorescent Protein (RFP) in transformated BL-21 strains of E. coli and p53 protein of MCF-7 were examined after exposure to sounds of specific frequencies.

Results: Through the exposure of the experimental systems to a sequence of sounds that match the frequencies of specific amino acids, the levels of RFP exhibition respective to the control groups in the bacterial medium increased two-fold in terms of RFU. The experiments that targeted the p53 protein with the 'music' showed a decrease in the cell prevalence in the MCF-7 type breast cancer cells by 28%, by decreasing the speed of tumour formation.

Conclusion: Exposure to 'music' that was designed through assigning a musical note for every single one of the twenty unique amino acids, produced both an analytical and a visible shift in protein synthesis, making it as potential tool for reducing procedural time uptake.

MeSH terms

  • Amino Acids / chemistry*
  • Cell Line, Tumor
  • Cytosol / metabolism*
  • Escherichia coli / metabolism
  • Gene Expression Regulation*
  • Humans
  • Luminescent Proteins / metabolism
  • MCF-7 Cells
  • Music*
  • Protein Biosynthesis*
  • RNA, Transfer / chemistry
  • Time Factors
  • Tumor Suppressor Protein p53 / metabolism


  • Amino Acids
  • Luminescent Proteins
  • TP53 protein, human
  • Tumor Suppressor Protein p53
  • red fluorescent protein
  • RNA, Transfer