Platelet-Rich Plasma in Androgenic Alopecia: Indications, Technique, and Potential Benefits

J Oral Maxillofac Surg. 2017 Apr;75(4):788-795. doi: 10.1016/j.joms.2016.10.040. Epub 2016 Nov 15.

Abstract

Purpose: The purpose of this study was to provide an overview of platelet-rich plasma (PRP) injected into the scalp for the management of androgenic alopecia.

Materials and methods: A literature review was performed to evaluate the benefits of PRP in androgenic alopecia.

Results: Hair restoration has been increasing. PRP's main components of platelet-derived growth factor, transforming growth factor, and vascular endothelial growth factor have the potential to stimulate hard and soft tissue wound healing. In general, PRP showed a benefit on patients with androgenic alopecia, including increased hair density and quality. Currently, different PRP preparations are being used with no standard technique.

Conclusion: This review found beneficial effects of PRP on androgenic alopecia. However, more rigorous study designs, including larger samples, quantitative measurements of effect, and longer follow-up periods, are needed to solidify the utility of PRP for treating patients with androgenic alopecia.

Publication types

  • Review

MeSH terms

  • Alopecia / therapy*
  • Humans
  • Platelet-Rich Plasma*
  • Scalp