Scleroderma with Nodular Scleroderma

Case Rep Dermatol. 2016 Nov 14;8(3):303-310. doi: 10.1159/000452324. eCollection Sep-Dec 2016.


Background: Nodular scleroderma is a rare variant of scleroderma which can occur in connection with systemic sclerosis or morphea. A biopsy from the lesion can demonstrate the scleroderma pattern, i.e., keloid pattern or mixed type. Treatment is challenging, and several treatments modalities have been reported with unsatisfactory results.

Main observations: We present a case of systemic sclerosis in a 50-year-old female who developed nodular scleroderma in the absence of deterioration of the scleroderma condition. Although no additional treatment was given, the lesions remained stable without progression.

Conclusions: Although this condition is rare, it has been reported sporadically, and clinicians should be able to recognize this variant in cases of scleroderma presenting with firm nodules or plaques.

Keywords: Keloidal scleroderma; Nodular scleroderma; Scleroderma.

Publication types

  • Case Reports