Acute Liver Failure Secondary to Hemophagocytic Lymphohistiocytosis during Pregnancy

ACG Case Rep J. 2016 Nov 23;3(4):e162. doi: 10.14309/crj.2016.135. eCollection 2016 Aug.

Abstract

Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of excessive immune activation that mimics and occurs with other systemic diseases. A 35-year-old female presented with signs of viral illness at 13 weeks of pregnancy and progressed to acute liver failure (ALF). We discuss the diagnosis of HLH and Kikuchi-Fujimoto (KF) lymphadenitis in the context of pregnancy and ALF. HLH may respond to comorbid disease-specific therapy, and more toxic treatment can be avoided.

Publication types

  • Case Reports