Paediatric renal tumours: perspectives from the SIOP-RTSG

Nat Rev Urol. 2017 Jan;14(1):3-4. doi: 10.1038/nrurol.2016.247. Epub 2016 Dec 6.


The >90% rates of overall survival for children with Wilms tumour are remarkable and have been achieved at the same time as reducing treatment for most patients. However, beneath this headline figure, 20% of patients still relapse after first-line therapy and up to 25% of survivors report severe late effects. The aim of the SIOP-RTSG is to improve outcomes and to reduce acute and late treatment toxic effects in all children.

MeSH terms

  • Child
  • Clinical Trials as Topic
  • Humans
  • Kidney Neoplasms / diagnosis
  • Kidney Neoplasms / drug therapy
  • Kidney Neoplasms / therapy*
  • Wilms Tumor / diagnosis
  • Wilms Tumor / drug therapy
  • Wilms Tumor / therapy*