Aplastic Anemia and MDS International Foundation (AAMDSIF): Bone marrow failure disease scientific symposium 2016

Leuk Res. 2017 Feb;53:8-12. doi: 10.1016/j.leukres.2016.11.011. Epub 2016 Nov 24.

Abstract

Patients with acquired and inherited bone marrow failure syndromes (BMFS) have ineffective hematopoiesis due to impairments of the hematopoietic stem cell compartment. Common manifestations of BMFS include varying degrees of peripheral blood cytopenias and, sometimes, progression to acute myelogenous leukemia. Research efforts have been made all over the world to improve understanding of the pathogenesis of these diseases and their clinical implications. The Aplastic Anemia and MDS International Foundation (AAMDSIF) is an independent nonprofit organization whose mission is to help patients and family members cope with BMFS. Here, we summarize recent scientific discoveries in several BMFS that were presented at the fifth International Bone Marrow Failure Disease Scientific Symposium 2016 that AAMDSIF sponsored on March 17-18, 2016, in Rockville, Maryland.

Keywords: Aplastic anemia; Bone marrow failure; Hematopoietic stem cell transplantation; Immunobiology; Myelodysplastic syndromes; Novel therapies.

Publication types

  • Review

MeSH terms

  • Anemia, Aplastic / pathology*
  • Anemia, Aplastic / therapy
  • Bone Marrow Diseases / pathology*
  • Bone Marrow Diseases / therapy
  • Bone Marrow Failure Disorders
  • Hematopoietic Stem Cells
  • Hemoglobinuria, Paroxysmal / pathology*
  • Hemoglobinuria, Paroxysmal / therapy
  • Humans
  • Myelodysplastic Syndromes / pathology
  • Myelodysplastic Syndromes / therapy

Supplementary concepts

  • Bone Marrow failure syndromes