Residential Proximity to Gasoline Stations and Risk of Childhood Leukemia

Am J Epidemiol. 2017 Jan 1;185(1):1-4. doi: 10.1093/aje/kww130. Epub 2016 Dec 6.


Significant elevations in the risk of childhood leukemia have been associated with environmental exposure to gasoline; aromatic hydrocarbons from refinery pollution, petroleum waste sites, and mobile sources (automobile exhaust); paints, paint products, and thinners; and secondary cigarette smoke in the home. These higher risks have also been associated with parental exposure to benzene, gasoline, motor vehicle-related jobs, painting, and rubber solvents. These exposures and jobs have 1 common chemical exposure-benzene, a recognized cause of acute leukemia in adults-and raise the question of whether children represent a subpopulation in which a higher risk of leukemia is associated with very low level exposure to environmental benzene.

Keywords: benzene; childhood leukemia; gasoline; gasoline stations; residential exposure.

Publication types

  • Comment

MeSH terms

  • Benzene / analysis
  • Environmental Exposure / analysis
  • Gasoline / analysis*
  • Humans
  • Leukemia
  • Vehicle Emissions*


  • Gasoline
  • Vehicle Emissions
  • Benzene