Seroepidemiology of human parechovirus types 1, 3, and 6 in Yamagata, Japan, in 2014

Microbiol Immunol. 2016 Dec;60(12):854-858. doi: 10.1111/1348-0421.12456.

Abstract

To clarify the seroepidemiology of human parechovirus type 1 (HPeV1), 3 and 6, neutralizing antibodies (NT Abs) were measured in 214 serum specimens collected in 2014 in Yamagata, Japan. The seroprevalence against HPeV1 was 100% in all age groups, while that against HPeV3 and HPeV6 was 79.4% and 66.8%, respectively, overall. The geometric mean titers of NT Abs against HPeV1, 3 and 6 were 755.2, 255.0 and 55.9, respectively, overall. Our findings indicate that HPeV1 is the most prevalent HPeV circulating in Yamagata, followed by HPeV3 and HPeV6.

Keywords: emerging disease; human parechovirus; seroepidemiology.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Antibodies, Neutralizing / blood*
  • Antibodies, Viral / blood*
  • Child
  • Child, Preschool
  • Female
  • Genotype
  • Humans
  • Infant
  • Infant, Newborn
  • Japan / epidemiology
  • Male
  • Middle Aged
  • Molecular Epidemiology
  • Parechovirus / immunology*
  • Picornaviridae Infections / epidemiology*
  • Seroepidemiologic Studies
  • Young Adult

Substances

  • Antibodies, Neutralizing
  • Antibodies, Viral