Efficacy of a gender-tailored intervention to prevent weight regain in men over 3 years: A weight loss maintenance RCT

Obesity (Silver Spring). 2017 Jan;25(1):56-65. doi: 10.1002/oby.21696. Epub 2016 Dec 7.

Abstract

Objective: To examine whether a gender-tailored weight loss maintenance (WLM) program could reduce men's weight regain following weight loss.

Methods: Ninety-two men who lost at least 4 kg during a 3-month weight loss phase were randomized to receive: (i) a 6-month WLM program (WL + WLM; n = 47) or (ii) no resources (WL-only; n = 45). The WLM program included written materials and messages (SMS, video email) plus other resources (e.g., pedometer, Gymstick™). The primary outcome was weight change in the first year post-randomization. Participants were assessed at "-3 months" (preweight loss), "0 months" (randomization into the WLM Phase), "6 months," "1 year," and "3 years."

Results: Before randomization, participants lost a mean (SD) of 7.3 kg (2.5). Retention was 83% at 6 months and 1 year and 71% at 3 years. Intention-to-treat analysis detected a significant group × time difference in weight regain favoring the intervention group at 6 months (-1.9 kg, 95% CI -3.7 to -0.1) but not at 1- or 3-year follow-up. Three years after completing the original weight loss program the WL-only and WL + WLM groups had maintained 59% and 51% of their initial weight loss, respectively.

Conclusions: Men with overweight/obesity demonstrated clinically meaningful WLM 3 years after successfully losing weight. An additional WLM program contributed to enhanced WLM effects in the short term only. (ACTRN12612000749808).

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Diet, Reducing
  • Humans
  • Male
  • Middle Aged
  • Obesity / therapy*
  • Physical Fitness*
  • Risk Reduction Behavior
  • Weight Loss*
  • Weight Reduction Programs / methods*
  • Young Adult

Associated data

  • ANZCTR/ACTRN12612000749808