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Review
. 2016 Dec 9;119(12):1280-1282.
doi: 10.1161/CIRCRESAHA.116.309942.

Exosomes: What Do We Love So Much About Them?

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Free PMC article
Review

Exosomes: What Do We Love So Much About Them?

Michael E Davis. Circ Res. .
Free PMC article

Abstract

Exosomes, once thought to be biomarkers of a diseased state are now thought to be biologically active and some of the paracrine effects of stem cell therapy. While there is much excitement around their actions, there is also a growing need to better understand the role of cell source, exosome content, and exosome targeting in a quantitative manner. Better understanding of these variables and others, in a reproducible and comprehensive approach, could better inform future therapy.

Keywords: biomarkers; cardiovascular system; exosome; microRNA; systems biology.

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