[Neurobiological aspects of personality disorders and emotional instability]

Lakartidningen. 2016 Dec 6;113:D43C.
[Article in Swedish]

Abstract

Neurobiological aspects of personality disorders and emotional instability ADHD and mental disorders encompassing emotional instability such as emotionally unstable personality disorder and antisocial personality disorder can potentially be explained by a suboptimal regulation of information processing in the brain. ADHD involves suboptimal function of non-emotional attentional regulatory processes and emotional instability involves suboptimal emotional regulation. A network including prefrontal areas, anterior cingulate cortex, basal ganglia and specific neuromodulatory systems such as the dopamine system are dysfunctional in both ADHD and emotional instability. One might suggest that a dimensional view better describes these mental states than categorical diagnoses.

Publication types

  • Review

MeSH terms

  • Attention Deficit Disorder with Hyperactivity / physiopathology*
  • Cerebral Cortex / physiopathology*
  • Emotions / physiology*
  • Female
  • Humans
  • Male
  • Personality Disorders / physiopathology*
  • Sex Factors