Public variant databases: liability?

Genet Med. 2017 Jul;19(7):838-841. doi: 10.1038/gim.2016.189. Epub 2016 Dec 15.


Public variant databases support the curation, clinical interpretation, and sharing of genomic data, thus reducing harmful errors or delays in diagnosis. As variant databases are increasingly relied on in the clinical context, there is concern that negligent variant interpretation will harm patients and attract liability. This article explores the evolving legal duties of laboratories, public variant databases, and physicians in clinical genomics and recommends a governance framework for databases to promote responsible data sharing.Genet Med advance online publication 15 December 2016.

MeSH terms

  • Data Curation / standards
  • Databases, Genetic / ethics*
  • Databases, Genetic / legislation & jurisprudence*
  • Databases, Genetic / statistics & numerical data
  • Databases, Nucleic Acid / ethics*
  • Databases, Nucleic Acid / legislation & jurisprudence
  • Databases, Nucleic Acid / trends
  • Genetic Variation
  • Genomics / ethics
  • Genomics / legislation & jurisprudence
  • Humans
  • Information Dissemination / ethics
  • Information Dissemination / legislation & jurisprudence