Abstract
Viruses have evolved a remarkable array of strategies to escape the host's innate immune responses. In this issue of Cell Host & Microbe, Zhao et al. (2016b) reveal a viral strategy to inactivate RIG-I signaling that relies on deamidation of RIG-I.
Copyright © 2016 Elsevier Inc. All rights reserved.
MeSH terms
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Adenosine Triphosphate / metabolism
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DEAD Box Protein 58 / immunology*
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Herpes Simplex / immunology
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Herpesvirus 1, Human / immunology*
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Immunity, Innate*
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Interferon Regulatory Factor-3 / metabolism
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Interferon Regulatory Factor-7 / metabolism
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NF-kappa B / metabolism
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Polyubiquitin / pharmacology
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Receptors, Immunologic
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Signal Transduction / immunology*
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TNF Receptor-Associated Factor 6 / metabolism
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Viral Structural Proteins / immunology
Substances
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IRF3 protein, human
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IRF7 protein, human
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Interferon Regulatory Factor-3
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Interferon Regulatory Factor-7
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NF-kappa B
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Receptors, Immunologic
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TNF Receptor-Associated Factor 6
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UL37 protein, Human herpesvirus 1
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Viral Structural Proteins
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Polyubiquitin
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Adenosine Triphosphate
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RIGI protein, human
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DEAD Box Protein 58