Synthesis of aza-crown analogues and macrocyclic bis-lactams with sucrose scaffold

Carbohydr Res. 2017 Jan 13;438:44-57. doi: 10.1016/j.carres.2016.12.001. Epub 2016 Dec 5.


2,3,3',4,4'-Penta-O-benzylsucrose was converted into the corresponding diaminoalcohol which was used as a key building block in the synthesis of the analogues of aza-crown ethers and bis-lactams.

Keywords: Aza-crown ether analogues; Macrocyclic bis-lactams; Selective functionalization; Sucrose.

MeSH terms

  • Catalysis
  • Crown Compounds / chemical synthesis*
  • Lactams, Macrocyclic / chemical synthesis*
  • Molecular Structure
  • Sucrose / chemistry*


  • Crown Compounds
  • Lactams, Macrocyclic
  • Sucrose