Bursts of Reprogramming: A Path to Extend Lifespan?

Cell. 2016 Dec 15;167(7):1672-1674. doi: 10.1016/j.cell.2016.11.050.

Abstract

In a thought-provoking study, Ocampo et al. show that the cyclic expression of stem cell reprogramming factors in vivo increases the lifespan of a mouse model of premature aging and provides health benefits to chronologically old, normal mice.

MeSH terms

  • Aging / metabolism*
  • Animals
  • Cellular Reprogramming*
  • Mice