The Management of Nausea and Vomiting of Pregnancy

J Obstet Gynaecol Can. 2016 Dec;38(12):1127-1137. doi: 10.1016/j.jogc.2016.08.009.


Objectives: To review the evidence-based management of nausea and vomiting of pregnancy and hyperemesis gravidarum.

Evidence: MEDLINE and Cochrane database searches were performed using the medical subject headings of treatment, nausea, vomiting, pregnancy, and hyperemesis gravidarum. The quality of evidence reported in these guidelines has been described using the Evaluation of Evidence criteria outlined in the Report of the Canadian Task Force on Preventative Health Care.

Benefits: Nausea and vomiting of pregnancy has a profound effect on women's health and quality of life during pregnancy as well as a financial impact on the health care system, and its early recognition and management is recommended. COST: Costs, including hospitalizations, additional office visits, and time lost from work, may be reduced if nausea and vomiting in pregnancy is treated early.

Keywords: Nausea; hyperemesis gravidarum; pharmacology; pregnancy; teratogenicity; treatment; vomiting.

Publication types

  • Practice Guideline

MeSH terms

  • Canada
  • Female
  • Humans
  • Hyperemesis Gravidarum / therapy*
  • Nausea / therapy*
  • Pregnancy