The prevalence of dyslipidemia and associated factors in children and adolescents with type 1 diabetes

J Pediatr Endocrinol Metab. 2017 Feb 1;30(2):181-187. doi: 10.1515/jpem-2016-0111.

Abstract

Background: Dyslipidemia increases the frequency and severity of micro and macrovascular complications of type 1 diabetes (T1D). The present study aims to determine the prevalence of dyslipidemia and its association with clinical and laboratory findings in diabetic children and adolescents.

Methods: The study included 202 children and adolescents with T1D. Demographic data and laboratory findings were obtained from patients files.

Results: Dyslipidemia prevalence was found to be 26.2%. Hypercholesterolemia (15.8%) and hyperglyceridemia (12.9%) were most common findings. Age, body mass index (BMI), hemoglobin A1c (A1C) and poor metabolic control were significantly higher in cases with dyslipidemia. Smoking rate was 14.1% in the pubertal group. Poor metabolic control and dyslipidemia was found higher among smokers (p<0.05).

Conclusions: Blood lipid levels should be monitored regularly and nutrition education should be repeated periodically to prevent and control dyslipidemia in patients with T1D. Smoking-related risks should be a part of patient education in the pubertal period.

MeSH terms

  • Adolescent
  • Biomarkers / blood*
  • Child
  • Diabetes Mellitus, Type 1 / complications*
  • Dyslipidemias / blood
  • Dyslipidemias / epidemiology*
  • Female
  • Follow-Up Studies
  • Glycated Hemoglobin A / analysis
  • Humans
  • Lipids / blood*
  • Male
  • Prevalence
  • Prognosis
  • Risk Factors
  • Turkey / epidemiology

Substances

  • Biomarkers
  • Glycated Hemoglobin A
  • Lipids