RNA Transport: From Head to Toe in Radial Glial Cells

Curr Biol. 2016 Dec 19;26(24):R1285-R1287. doi: 10.1016/j.cub.2016.11.017.

Abstract

Intracellular mRNA localization critically contributes to proper brain development and function. A recent study demonstrates that mRNAs are actively transported in radial glial cells from the soma to the distal basal endfeet, where they are locally translated.

Publication types

  • Comment

MeSH terms

  • Animals
  • Biological Transport / physiology
  • Brain / embryology
  • Brain / metabolism
  • Ependymoglial Cells / physiology*
  • Gene Expression Regulation, Developmental / physiology
  • Mammals / embryology*
  • RNA, Messenger / genetics
  • RNA, Messenger / metabolism*

Substances

  • RNA, Messenger