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. 2016 Dec 20;45(6):1184-1186.
doi: 10.1016/j.immuni.2016.12.005.

Sifting Through CD8 + T Cell Memory


Sifting Through CD8 + T Cell Memory

Matthew D Martin et al. Immunity. .


In this issue of Immunity, Gerlach et al. (2016) describe three distinct memory CD8+ T cell subsets based upon expression of the fractalkine receptor CX3CR1. Their findings revise the paradigm of effector and central memory T cells by revealing a subset of CD8+ memory T cells defined by intermediate levels of expression of CX3CR1 that conducts tissue surveillance.

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