Sifting through CD8 + T Cell Memory

Immunity. 2016 Dec 20;45(6):1184-1186. doi: 10.1016/j.immuni.2016.12.005.


In this issue of Immunity, Gerlach et al. (2016) describe three distinct memory CD8+ T cell subsets based upon expression of the fractalkine receptor CX3CR1. Their findings revise the paradigm of effector and central memory T cells by revealing a subset of CD8+ memory T cells defined by intermediate levels of expression of CX3CR1 that conducts tissue surveillance.

Publication types

  • Comment

MeSH terms

  • CD8-Positive T-Lymphocytes / immunology*
  • Immunologic Memory / immunology*
  • T-Lymphocyte Subsets / immunology