Maintaining hair follicle stem cell identity in a dish

EMBO J. 2017 Jan 17;36(2):132-134. doi: 10.15252/embj.201696051. Epub 2016 Dec 21.


Identifying and mimicking the signals that regulate stem cell self‐renewal, differentiation and maintenance in a petri dish is crucial to faithfully recapitulate stem cell behaviour in vitro. In this issue, Chacón‐Martínez et al (2017) describe novel culture conditions that allow the long‐term expansion and maintenance of functional murine hair follicle stem cells. This exciting discovery provides a faithful platform to study hair follicle stem cells in vitro and potentially perform drug screening for skin and hair follicle disorders.

Publication types

  • Comment

MeSH terms

  • Cell Cycle
  • Hair Follicle*
  • Humans
  • Stem Cells*