Interrogating cellular perception and decision making with optogenetic tools

J Cell Biol. 2017 Jan 2;216(1):25-28. doi: 10.1083/jcb.201612094. Epub 2016 Dec 21.

Abstract

Optogenetics promises to deepen our understanding of how cells perceive and respond to complex and dynamic signals and how this perception regulates normal and abnormal function. In this study, we present our vision for how these nascent tools may transform our view of fundamental cell biological processes.

MeSH terms

  • Animals
  • Cell Biology / trends*
  • Diffusion of Innovation
  • Forecasting
  • Gene Regulatory Networks
  • Humans
  • Optogenetics / trends*
  • Protein Interaction Maps
  • Signal Transduction*