Contrasting effects of myeloid and endothelial ADAM17 on atherosclerosis development

Thromb Haemost. 2017 Feb 28;117(3):644-646. doi: 10.1160/TH16-09-0674. Epub 2016 Dec 22.

Authors

Emiel P C van der Vorst¹, Zhen Zhao, Martina Rami, Lesca M Holdt, Daniel Teupser, Sabine Steffens, Christian Weber²

Affiliations

¹ Dr. Emiel P. C. van der Vorst, Institute for Cardiovascular Prevention, Pettenkoferstrasse 9, 80336 Munich, Germany, Tel. +49 89 4400 54633, Fax: + 49 89 4400 54352, E-mail: Emiel.Van_der_Vorst@med.uni-muenchen.de.
² Univ.-Prof. Dr. med. Christian Weber, Institute for Cardiovascular Prevention, Pettenkoferstrasse 9, 80336 Munich, Germany, Tel. +49 89 4400 54633, Fax: + 49 89 4400 54352, E-mail: Christian.Weber@med.uni-muenchen.de.

PMID: 28004058
DOI: 10.1160/TH16-09-0674

No abstract available

Publication types

Comparative Study
Letter
Research Support, Non-U.S. Gov't

MeSH terms

ADAM17 Protein / deficiency
ADAM17 Protein / genetics
ADAM17 Protein / metabolism*
Animals
Atherosclerosis / enzymology*
Atherosclerosis / genetics
Atherosclerosis / pathology
Atherosclerosis / prevention & control
Collagen / metabolism
Diet, High-Fat
Disease Models, Animal
Disease Progression
Endothelial Cells / enzymology*
Genetic Predisposition to Disease
Mice, Knockout
Mice, Knockout, ApoE
Myeloid Cells / enzymology*
Phenotype
Plaque, Atherosclerotic*
Time Factors

Substances

Collagen
ADAM17 Protein
Adam17 protein, mouse