Discriminating between first- and second-order cognition in first-episode paranoid schizophrenia

Cogn Neuropsychiatry. 2017 Mar;22(2):95-107. doi: 10.1080/13546805.2016.1268954. Epub 2016 Dec 22.

Abstract

Introduction: An impairment of visually perceiving backward masked stimuli is commonly observed in patients with schizophrenia, yet it is unclear whether this impairment is the result of a deficiency in first or higher order processing and for which subtypes of schizophrenia it is present.

Methods: Here, we compare identification (first order) and metacognitive (higher order) performance in a visual masking paradigm between a highly homogenous group of young first-episode patients diagnosed with paranoid schizophrenia (N = 11) to that of carefully matched healthy controls (N = 13).

Results: We find no difference across groups in first-order performance, but find a difference in metacognitive performance, particularly for stimuli with relatively high visibility.

Conclusions: These results indicate that the masking deficit is present in first-episode patients with paranoid schizophrenia, but that it is primarily an impairment of metacognition.

Keywords: Visual perception; cognition; first-episode; metacognition; paranoia; schizophrenia.

MeSH terms

  • Adult
  • Case-Control Studies
  • Cognition Disorders / complications
  • Cognition Disorders / psychology*
  • Female
  • Humans
  • Male
  • Perceptual Masking*
  • Psychometrics*
  • Schizophrenia, Paranoid / complications
  • Schizophrenia, Paranoid / psychology*
  • Schizophrenic Psychology
  • Young Adult