Rubber: new allergens and preventive measures

Eur J Dermatol. 2016 Dec 1;26(6):523-530. doi: 10.1684/ejd.2016.2839.

Abstract

Natural rubber latex (NRL) and rubber accelerators are well-known causes of occupational skin diseases. The latest epidemiological data on rubber allergy show that rubber additives are still among the allergens most strongly associated with occupational contact dermatitis, however, a decrease in NRL allergy has been confirmed. A review of recent publications on rubber allergens based on the Pubmed database is presented. New glove manufacturing processes have been developed, such as low-protein natural rubber gloves, vulcanisation accelerator-free gloves, or specific-purpose gloves containing antimicrobial agents or moisturisers. Several websites provide information on allergens found in gloves and/or glove choice according to occupation.

Keywords: allergen; allergy; contact dermatitis; glove; latex; rubber.

Publication types

  • Review

MeSH terms

  • Allergens / adverse effects*
  • Gloves, Protective*
  • Guanidines / immunology
  • Humans
  • Latex Hypersensitivity / epidemiology*
  • Latex Hypersensitivity / prevention & control*
  • Rubber / adverse effects*
  • Rubber / chemical synthesis
  • Thiourea / analogs & derivatives
  • Thiourea / immunology
  • Thiram / analogs & derivatives
  • Thiram / immunology

Substances

  • Allergens
  • Guanidines
  • Thiram
  • Rubber
  • Thiourea