The PPI3D web server for searching, analyzing and modeling protein-protein interactions in the context of 3D structures

Justas Dapkunas; Albertas Timinskas; Kliment Olechnovic; Mindaugas Margelevicius; Rytis Diciunas; Ceslovas Venclovas

doi:10.1093/bioinformatics/btw756

The PPI3D web server for searching, analyzing and modeling protein-protein interactions in the context of 3D structures

Bioinformatics. 2017 Mar 15;33(6):935-937. doi: 10.1093/bioinformatics/btw756.

Authors

Justas Dapkunas¹, Albertas Timinskas¹, Kliment Olechnovic^{1

2}, Mindaugas Margelevicius¹, Rytis Diciunas¹, Ceslovas Venclovas¹

Affiliations

¹ Institute of Biotechnology, Vilnius University, Vilnius, Lithuania.
² Faculty of Mathematics and Informatics, Vilnius University, Vilnius, Lithuania.

PMID: 28011769
DOI: 10.1093/bioinformatics/btw756

Abstract

Summary: The PPI3D web server is focused on searching and analyzing the structural data on protein-protein interactions. Reducing the data redundancy by clustering and analyzing the properties of interaction interfaces using Voronoi tessellation makes this software a highly effective tool for addressing different questions related to protein interactions.

Availability and implementation: The server is freely accessible at http://bioinformatics.lt/software/ppi3d/ .

Contact: ceslovas.venclovas@bti.vu.lt.

Supplementary information: Supplementary data are available at Bioinformatics online.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Internet
Models, Molecular*
Protein Binding
Protein Conformation
Proteins / chemistry*
Proteins / metabolism
Software*

Substances

Proteins