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Editorial
. 2016 Dec 29;375(26):2596-8.
doi: 10.1056/NEJMe1611723.

Breathing Easier with Fish Oil - A New Approach to Preventing Asthma?

Christopher E Ramsden  1
Affiliations
Editorial

Breathing Easier with Fish Oil - A New Approach to Preventing Asthma?

Christopher E Ramsden. N Engl J Med. .
No abstract available

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Figures

Figure 1
Figure 1. Model Depicting Fish Oil–Induced Alterations in Lipid Mediators of Inflammation and Bronchoconstriction
Leukotrienes synthesized from arachidonic acid mediate bronchoconstriction and airway inflammation (Panel A). The docosahexaenoic acid and eicosapentaenoic acid in fish oil displace arachidonic acid in membrane phospholipids, which serve as precursors for biosynthesis of lipid mediators. This effect shifts the balance away from mediators of inflammation and bronchoconstriction and toward the resolution of inflammation and host defense (Panel B).
See this image and copyright information in PMC

Comment in

  • Recent advances in asthma.
    Chipps BE, Dinakar C, Fineman SM, Tilles SA. Chipps BE, et al. Ann Allergy Asthma Immunol. 2018 Feb;120(2):128-130. doi: 10.1016/j.anai.2017.12.015. Ann Allergy Asthma Immunol. 2018. PMID: 29413335 No abstract available.

Comment on

  • Fish Oil-Derived Fatty Acids in Pregnancy and Wheeze and Asthma in Offspring.
    Bisgaard H, Stokholm J, Chawes BL, Vissing NH, Bjarnadóttir E, Schoos AM, Wolsk HM, Pedersen TM, Vinding RK, Thorsteinsdóttir S, Følsgaard NV, Fink NR, Thorsen J, Pedersen AG, Waage J, Rasmussen MA, Stark KD, Olsen SF, Bønnelykke K. Bisgaard H, et al. N Engl J Med. 2016 Dec 29;375(26):2530-9. doi: 10.1056/NEJMoa1503734. N Engl J Med. 2016. PMID: 28029926 Clinical Trial.

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