Implementation of Rapid Molecular Infectious Disease Diagnostics: the Role of Diagnostic and Antimicrobial Stewardship

J Clin Microbiol. 2017 Mar;55(3):715-723. doi: 10.1128/JCM.02264-16. Epub 2016 Dec 28.


New rapid molecular diagnostic technologies for infectious diseases enable expedited accurate microbiological diagnoses. However, diagnostic stewardship and antimicrobial stewardship are necessary to ensure that these technologies conserve, rather than consume, additional health care resources and optimally affect patient care. Diagnostic stewardship is needed to implement appropriate tests for the clinical setting and to direct testing toward appropriate patients. Antimicrobial stewardship is needed to ensure prompt appropriate clinical action to translate faster diagnostic test results in the laboratory into improved outcomes at the bedside. This minireview outlines the roles of diagnostic stewardship and antimicrobial stewardship in the implementation of rapid molecular infectious disease diagnostics.

Keywords: antimicrobial stewardship; appropriate use criteria; diagnostic stewardship; implementation; rapid diagnostics; utilization.

Publication types

  • Review

MeSH terms

  • Anti-Infective Agents / therapeutic use*
  • Communicable Diseases / diagnosis*
  • Communicable Diseases / drug therapy*
  • Drug Utilization / standards*
  • Early Diagnosis
  • Humans
  • Microbial Sensitivity Tests / methods*
  • Molecular Diagnostic Techniques / methods*
  • Time Factors


  • Anti-Infective Agents