Treatment of Methicillin-Resistant Staphylococcus aureus Bacteremia
- PMID: 28032484
- PMCID: PMC5204005
- DOI: 10.3947/ic.2016.48.4.267
Treatment of Methicillin-Resistant Staphylococcus aureus Bacteremia
Abstract
Methicillin-resistant Staphylococcus aureus (MRSA) is a significant cause of health care-associated infections. Vancomycin remains an acceptable treatment option. There has been a welcome increase in the number of agents available for the treatment of MRSA infection. These drugs have certain differentiating attributes and may offer some advantages over vancomycin, but they also have significant limitations. These agents provide some alternative when no other options are available.
Keywords: Methicillin-resistant Staphylcoccus aureus; Treatment; Vancomycin.
Conflict of interest statement
No conflicts of interest.
Similar articles
-
Predicting methicillin resistance and the effect of inadequate empiric therapy on survival in patients with Staphylococcus aureus bacteremia.Arch Intern Med. 2000 Apr 10;160(7):1001-4. doi: 10.1001/archinte.160.7.1001. Arch Intern Med. 2000. PMID: 10761966
-
Bacteremia due to Methicillin-Resistant Staphylococcus aureus: New Therapeutic Approaches.Infect Dis Clin North Am. 2016 Jun;30(2):491-507. doi: 10.1016/j.idc.2016.02.009. Infect Dis Clin North Am. 2016. PMID: 27208769 Review.
-
Treatment of methicillin-resistant Staphylococcus aureus: vancomycin and beyond.Semin Respir Crit Care Med. 2015 Feb;36(1):17-30. doi: 10.1055/s-0034-1397040. Epub 2015 Feb 2. Semin Respir Crit Care Med. 2015. PMID: 25643268 Review.
-
A randomized phase 2B trial of vancomycin versus daptomycin for the treatment of methicillin-resistant Staphylococcus aureus bacteremia due to isolates with high vancomycin minimum inhibitory concentrations - results of a prematurely terminated study.Trials. 2018 Jun 1;19(1):305. doi: 10.1186/s13063-018-2702-8. Trials. 2018. PMID: 29859132 Free PMC article. Clinical Trial.
-
Using MRSA Screening Tests To Predict Methicillin Resistance in Staphylococcus aureus Bacteremia.Antimicrob Agents Chemother. 2016 Nov 21;60(12):7444-7448. doi: 10.1128/AAC.01751-16. Print 2016 Dec. Antimicrob Agents Chemother. 2016. PMID: 27736763 Free PMC article.
Cited by
-
PDADMAC/Alginate-Coated Gold Nanorod For Eradication of Staphylococcus Aureus Biofilms.Int J Nanomedicine. 2024 Apr 23;19:3697-3714. doi: 10.2147/IJN.S452085. eCollection 2024. Int J Nanomedicine. 2024. PMID: 38681091 Free PMC article.
-
Recent Advances in the Development of Antibiotics-Coated Gold Nanoparticles to Combat Antimicrobial Resistance.Antibiotics (Basel). 2024 Jan 26;13(2):124. doi: 10.3390/antibiotics13020124. Antibiotics (Basel). 2024. PMID: 38391510 Free PMC article. Review.
-
Population Pharmacokinetics and Model-Based Dose Optimization of Vancomycin in Sudanese Adult Patients with Renal Impairment.Drug Des Devel Ther. 2024 Jan 16;18:81-95. doi: 10.2147/DDDT.S432439. eCollection 2024. Drug Des Devel Ther. 2024. PMID: 38260090 Free PMC article.
-
Nanosecond pulsed electric fields increase antibiotic susceptibility in methicillin-resistant Staphylococcus aureus.Microbiol Spectr. 2024 Jan 11;12(1):e0299223. doi: 10.1128/spectrum.02992-23. Epub 2023 Dec 4. Microbiol Spectr. 2024. PMID: 38092563 Free PMC article.
-
Electrospun PCL Wires Loaded with Vancomycin on Zirconium Substrate.Materials (Basel). 2023 Nov 20;16(22):7237. doi: 10.3390/ma16227237. Materials (Basel). 2023. PMID: 38005168 Free PMC article.
References
-
- Liu C, Bayer A, Cosgrove SE, Daum RS, Fridkin SK, Gorwitz RJ, Kaplan SL, Karchmer AW, Levine DP, Murray BE. J Rybak M, Talan DA, Chambers HF; Infectious Diseases Society of America. Clinical practice guidelines by the infectious diseases society of america for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children. Clin Infect Dis. 2011;52:e18–55. - PubMed
-
- Kalil AC, Van Schooneveld TC, Fey PD, Rupp ME. Association between vancomycin minimum inhibitory concentration and mortality among patients with Staphylococcus aureus bloodstream infections: a systematic review and meta-analysis. JAMA. 2014;312:1552–1564. - PubMed
-
- Zelenitsky S, Rubinstein E, Ariano R, Iacovides H, Dodek P, Mirzanejad Y, Kumar A, Cooperative Antimicrobial Therapy of Septic Shock-CATSS Database Research Group Vancomycin pharmacodynamics and survival in patients with methicillin-resistant Staphylococcus aureus-associated septic shock. Int J Antimicrob Agents. 2013;41:255–260. - PubMed
-
- Cavalcanti AB, Goncalves AR, Almeida CS, Bugano DD, Silva E. Teicoplanin versus vancomycin for proven or suspected infection. Cochrane Database Syst Rev. 2010:CD007022. - PubMed
Publication types
LinkOut - more resources
Full Text Sources
Other Literature Sources
