Common Arterial Trunk Repair by Means of a Handmade Bovine Pericardial-Valved Woven Dacron Conduit

World J Pediatr Congenit Heart Surg. 2017 Jan;8(1):69-76. doi: 10.1177/2150135116674439.

Abstract

Background: Surgical repair of common arterial trunk (CAT) by means of a homograft conduit has become a standard practice. We report our experience in the correction of this heart disease with a handmade bovine pericardial-valved woven Dacron conduit as an alternative procedure to homografts, with a focus on early, mid-term, and long-term results.

Methods: We designed a retrospective study that included 15 patients with a mean age of 1.5 years (range: three months to eight years), who underwent primary repair of simple CAT. Right ventricular outflow tract was reconstructed in all the cases with this handmade graft that was explanted at the time of its biological stenotic degeneration. A peeling procedure was performed at this time, in order to reconstruct the right ventricle-to-pulmonary artery continuity.

Results: Overall mortality was 13.3% (one death at the early postoperative primary repair and the other at the mid-term postoperative peeling reoperation). Actuarial survival rate was 93.3%, 86.7%, and 86.7% at 5, 10, and 15 years, respectively. All of the 14 survivors developed stenosis of the handmade conduit at the mid-term period (8 ± 3 years), but after the peeling procedure, 13 survivors remain asymptomatic to date.

Conclusions: Primary repair of common arterial trunk using a handmade conduit can be performed with very low perioperative mortality and satisfactory mid-term and long-term results, which can be favorably compared with those reported with the use of homografts. When graft obstruction develops, peeling procedure is a good option because it does not affect the overall survival, although long-term outcomes warrant further follow-up.

Keywords: congenital heart disease; homografts; surgery; truncus arteriosus.

Publication types

  • Observational Study

MeSH terms

  • Animals
  • Cattle
  • Female
  • Follow-Up Studies
  • Humans
  • Infant
  • Male
  • Pericardium / transplantation*
  • Polyethylene Terephthalates*
  • Prostheses and Implants*
  • Prosthesis Design
  • Pulmonary Artery / surgery
  • Reoperation
  • Retrospective Studies
  • Survival Rate / trends
  • Transplantation, Homologous
  • Truncus Arteriosus / abnormalities
  • Truncus Arteriosus / surgery*
  • Truncus Arteriosus, Persistent / mortality
  • Truncus Arteriosus, Persistent / surgery*

Substances

  • Polyethylene Terephthalates