Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
, 496 (1-2), 357-60

Characteristics of the Bursting Pattern of Action Potentials That Occurs in the Thalamus of Patients With Central Pain

Affiliations

Characteristics of the Bursting Pattern of Action Potentials That Occurs in the Thalamus of Patients With Central Pain

F A Lenz et al. Brain Res.

Abstract

Neurons in the somatosensory thalamus of patients with central pain following spinal cord injury fire in bursts of action potentials more frequently than do similar neurons in patients without pain. Furthermore, the characteristic firing pattern within these bursts is similar to that which is shown to be associated with the occurrence of calcium spikes in intracellular studies of thalamic nuclei. This finding may have significant implications for the etiology and treatment of central pain states.

Similar articles

See all similar articles

Cited by 60 articles

See all "Cited by" articles

Publication types

LinkOut - more resources

Feedback