In 213 specimens of human milk from the first 10 days of lactation after delivery, the concentration of secretory immunoglobin A and its ratio in total milk protein and the lysozyme content were assessed. The dynamics of values were also assessed and a great individual variability was found. Because of the high content of secretory immunoglobulin A, lysozyme and other immune components in colostrum during the first 24 hours after delivery, the authors gave it the name of hyperimmune colostrum. They recommend to include it in the initial nutrition of all neonates as an effective anti-infections protection. They recommend to use this colostrum also in the treatment of enteral infections of all neonates and other infants.