The number of cancer survivors is estimated by 2022 to increase to almost 18 million, in part because of improvements in earlier detection and cancer therapies, leading to longer-term survival of cancer patients. This growing number of survivors has presented challenges to the healthcare community, one of which is the need to provide to the survivor a seamless transition from the oncologist to the primary care provider (PCP). A major national initiative is under way for oncologists to provide survivorship care plans to their patients and PCPs, with the aim of communicating a complete record of cancer treatment and guiding the PCP in the future care of these cancer survivors. In caring for cancer survivors, PCPs must be familiar with the long-term and late effects, both medical and psychosocial, that are associated with common cancer treatments as well as the oncologic diagnosis itself. This article provides a unique approach to the traditional history and physical of easing the transition to primary care after completing cancer therapy for the cancer survivor. The cancer survivor-focused history and physical provide the PCP with a familiar and efficient method to clinically evaluate cancer survivors that closes the gap in this important transition of care.