Oligonucleotide Therapeutics - A New Class of Cholesterol-Lowering Drugs

N Engl J Med. 2017 Jan 5;376(1):4-7. doi: 10.1056/NEJMp1614154.
No abstract available

MeSH terms

  • Acetylgalactosamine / chemistry
  • Acetylgalactosamine / therapeutic use
  • Anticholesteremic Agents* / therapeutic use
  • Drug Discovery*
  • Hepatocytes / metabolism
  • Humans
  • RNA, Small Interfering / chemistry
  • RNA, Small Interfering / therapeutic use*
  • RNAi Therapeutics*

Substances

  • ALN-PCS
  • Anticholesteremic Agents
  • RNA, Small Interfering
  • Acetylgalactosamine