Ribonuclease E: Chopping Knife and Sculpting Tool

Joel G Belasco

doi:10.1016/j.molcel.2016.12.015

Ribonuclease E: Chopping Knife and Sculpting Tool

Mol Cell. 2017 Jan 5;65(1):3-4. doi: 10.1016/j.molcel.2016.12.015.

Author

Joel G Belasco¹

Affiliation

¹ Kimmel Center for Biology and Medicine at the Skirball Institute and Department of Microbiology, New York University School of Medicine, 540 First Avenue, New York, NY 10016, USA. Electronic address: joel.belasco@med.nyu.edu.

Abstract

In this issue of Molecular Cell, Chao et al. (2017) investigate the important role of the low-specificity endonuclease RNase E in shaping the transcriptome of a bacterial pathogen by functioning as both a degradative enzyme and an RNA maturase.

Keywords: RNA decay; RNA degradation; RNA maturation; RNA processing; RNA stability; RNA-seq; RNase E; Salmonella; endoribonuclease; sRNA.

MeSH terms

Endoribonucleases / genetics
Escherichia coli / enzymology*
RNA, Bacterial
RNA, Messenger / genetics*

Substances

RNA, Bacterial
RNA, Messenger
Endoribonucleases
ribonuclease E

Abstract

MeSH terms

Substances

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