Optical coherence tomography angiography and fundus autofluorescence in the eyes with choroideremia

BMJ Case Rep. 2017 Jan 6;2017:bcr2016217682. doi: 10.1136/bcr-2016-217682.


A 65-year-old man with presumed choroideremia with preserved central vision was examined by fundus autofluorescence (FAF) and optical coherence tomography angiography (OCTA). FAF showed an isolated area of hyperautofluorescence that involved the fovea. Although the choroid capillary slab of the OCTA showed the medium and large choroidal vessels inferior to the area of retinal pigment epithelium (RPE) atrophy, the choriocapillaris was visible in a relatively wider area than the hyperautofluorescent area in the FAF images. FAF and OCTA images allowed us to detect damage of the RPE before the choriocapillaris atrophy in a case of presumed choroideremia with preserved central vision.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Choroideremia / diagnosis*
  • Choroideremia / physiopathology
  • Fluorescein Angiography / methods
  • Humans
  • Male
  • Multimodal Imaging
  • Optical Imaging / methods
  • Tomography, Optical Coherence / methods
  • Vision Disorders / etiology
  • Vision Disorders / physiopathology
  • Visual Acuity / physiology