Jasmonate signaling and manipulation by pathogens and insects

J Exp Bot. 2017 Mar 1;68(6):1371-1385. doi: 10.1093/jxb/erw478.


Plants synthesize jasmonates (JAs) in response to developmental cues or environmental stresses, in order to coordinate plant growth, development or defense against pathogens and herbivores. Perception of pathogen or herbivore attack promotes synthesis of jasmonoyl-L-isoleucine (JA-Ile), which binds to the COI1-JAZ receptor, triggering the degradation of JAZ repressors and induction of transcriptional reprogramming associated with plant defense. Interestingly, some virulent pathogens have evolved various strategies to manipulate JA signaling to facilitate their exploitation of plant hosts. In this review, we focus on recent advances in understanding the mechanism underlying the enigmatic switch between transcriptional repression and hormone-dependent transcriptional activation of JA signaling. We also discuss various strategies used by pathogens and insects to manipulate JA signaling and how interfering with this could be used as a novel means of disease control.

Keywords: Insect defense; jasmonate; plant hormone; plant immunity; plant pathogen; salicylic acid..

Publication types

  • Review
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cyclopentanes / metabolism*
  • Food Chain
  • Gene Expression Regulation, Plant*
  • Herbivory*
  • Insecta / physiology
  • Oxylipins / metabolism*
  • Plant Growth Regulators / metabolism*
  • Plant Physiological Phenomena*
  • Plants / microbiology*
  • Signal Transduction*


  • Cyclopentanes
  • Oxylipins
  • Plant Growth Regulators
  • jasmonic acid