Evaluation of Herpes Simplex Virus Type 2 Serological Tests for Use With Dried Blood Spots in Kenya

Sex Transm Dis. 2017 Feb;44(2):101-103. doi: 10.1097/OLQ.0000000000000557.

Abstract

We evaluated 2 assays to detect antibodies to herpes simplex virus type 2 in dried blood spots prepared from blood specimens submitted to a reference laboratory in Kenya. Dried blood spots did not perform well with the Kalon herpes simplex virus type 2 assay. Focus HerpeSelect 2 was 98.8% sensitive and 98.9% specific with dried blood spots.

Publication types

  • Evaluation Study

MeSH terms

  • Antibodies, Viral / blood*
  • Enzyme-Linked Immunosorbent Assay
  • Herpes Simplex / diagnosis*
  • Herpes Simplex / virology
  • Herpesvirus 2, Human / immunology*
  • Herpesvirus 2, Human / isolation & purification
  • Humans
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Serologic Tests

Substances

  • Antibodies, Viral