Can total bronchopleural fistulas from complete stump dehiscence be endoscopically treated?

Eur J Cardiothorac Surg. 2017 Apr 1;51(4):702-708. doi: 10.1093/ejcts/ezw377.

Abstract

Objectives: Bronchopleural fistula (BPF) is an uncommon complication following a lung resection to address various conditions. BPFs are associated with high morbidity and mortality rates. This study evaluated the endoscopic treatment of 'total' BPFs using the Occlutech-Fígulla® cardiac device at a single centre.

Methods: We selected nine patients with chronic and complete BPFs. Under direct bronchoscopic visualization, the BPFs were treated using the Occlutech-Fígulla device. The patients were followed up for 12 months to determine the treatment level and complications.

Results: The procedure had a favourable outcome in three patients, resulting in complete fistula closure. Two patients had partial closure and showed improvements in their clinical conditions. In two other cases, closure of the bronchial stump was unsuccessful using this method. Two patients died from causes unrelated to the procedure or the device. During the follow-up period, no complications related to infection or device-related injuries were reported.

Conclusions: In patients without clinical conditions that require surgical treatment, the Occlutech-Fígulla cardiac device can be a safe and effective method for the endoscopic treatment of large BPFs resulting from complete dehiscence of a bronchial stump. No severe events were reported.

Keywords: Bronchopleural fistula; Bronchoscopy; Equipment safety; Septal occluder device; Occlutech-figulla device Clinical registration number: ClinicalTrials.gov Identifier: NCT01153074.

Publication types

  • Clinical Trial

MeSH terms

  • Adult
  • Aged
  • Bronchial Fistula / etiology
  • Bronchial Fistula / surgery
  • Bronchoscopy / adverse effects
  • Bronchoscopy / methods*
  • Chronic Disease
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Pleural Diseases / etiology
  • Pleural Diseases / surgery
  • Pneumonectomy / adverse effects
  • Prospective Studies
  • Respiratory Tract Fistula / etiology*
  • Respiratory Tract Fistula / surgery*
  • Septal Occluder Device / adverse effects
  • Surgical Wound Dehiscence / complications*
  • Treatment Outcome