Whole-Genome Sequences of Mycobacterium tuberculosis TB282 and TB284, a Widespread and a Unique Strain, Respectively, Identified in a Previous Study of Tuberculosis Transmission in Central Los Angeles, California, USA

Lixin Zhang; Zhenhua Yang

doi:10.1128/genomeA.01418-16

Whole-Genome Sequences of Mycobacterium tuberculosis TB282 and TB284, a Widespread and a Unique Strain, Respectively, Identified in a Previous Study of Tuberculosis Transmission in Central Los Angeles, California, USA

Genome Announc. 2017 Jan 12;5(2):e01418-16. doi: 10.1128/genomeA.01418-16.

Authors

Lixin Zhang^{1

2}, Zhenhua Yang³

Affiliations

¹ Department of Epidemiology & Biostatistics, Michigan State University, East Lansing, Michigan, USA lxzhang@msu.edu.
² Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, USA.
³ Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA.

Abstract

We report here the genome sequences of two Mycobacterium tuberculosis clinical isolates previously identified in central Los Angeles, CA, in the 1990s using a PacBio platform. Isolate TB282 represents a large-cluster strain that caused 27% of the tuberculosis cases, while TB284 represents a strain that caused disease in only one patient.