Anatomical distribution and outcome of surgical excision of fibrokeratoma - a clinical analysis of 124 cases

Int J Dermatol. 2017 Mar;56(3):337-340. doi: 10.1111/ijd.13455. Epub 2017 Jan 13.


Background: Fibrokeratoma is a benign, cutaneous, fibrous tumor usually occurring on the digits. There is little data about their occurrence on nondigital areas and their surgical outcomes.

Objectives: We sought to retrospectively characterize the distribution and surgical outcome of fibrokeratoma.

Methods: We retrospectively reviewed the clinical information of patients with a histopathological diagnosis of fibrokeratoma, including age, gender, lesion site, number of lesions, symptoms and signs, history of trauma, and any recurrence.

Results: We identified 124 patients diagnosed with fibrokeratoma in a 13-year period. The mean age was 42 years. There was a male predilection (2 : 1), and all lesions were solitary. Twenty patients (16%) had symptoms, and 13 patients (10%) had a history of trauma. Thirty patients (24%) had lesions on nondigital areas, including the upper and lower extremities and buttocks. The overall recurrence rate was 4% (five cases). Among them, three recurrent lesions were located on the periungual area of the toe. Nine patients (7%) had giant fibrokeratoma (>1 cm) but none recurred.

Conclusion: Although most fibrokeratomas appeared on the digits, a certain number of cases (24%) were located on nondigital areas. The periungual area of the toe was the most common local recurrent site.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Buttocks
  • Child
  • Elbow
  • Female
  • Foot
  • Forearm
  • Hand
  • Humans
  • Keratosis / complications
  • Keratosis / pathology*
  • Keratosis / surgery*
  • Knee
  • Leg
  • Lower Extremity*
  • Male
  • Middle Aged
  • Recurrence
  • Retrospective Studies
  • Thigh
  • Upper Extremity*
  • Young Adult