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Comparative Study
. 2017 Jul;53(1):70-77.
doi: 10.1016/j.amepre.2016.11.009. Epub 2017 Jan 13.

Diabetes Prevention Program Translation in the Veterans Health Administration

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Free PMC article
Comparative Study

Diabetes Prevention Program Translation in the Veterans Health Administration

Tannaz Moin et al. Am J Prev Med. .
Free PMC article

Abstract

Introduction: This clinical demonstration trial compared the effectiveness of the Veterans Affairs Diabetes Prevention Program (VA-DPP) with an evidence-based usual care weight management program (MOVE!®) in the Veterans Health Administration health system.

Design: Prospective, pragmatic, non-randomized comparative effectiveness study of two behavioral weight management interventions.

Setting/participants: Obese/overweight Veterans with prediabetes were recruited from three geographically diverse VA sites between 2012 and 2014.

Intervention: VA-DPP included 22 group-based intensive lifestyle change sessions.

Main outcome measures: Weight change at 6 and 12 months, hemoglobin A1c (HbA1c) at 12 months, and VA health expenditure changes at 15 months were assessed using VA electronic health record and claims data. Between- and within-group comparisons for weight and HbA1c were done using linear mixed-effects models controlling for age, gender, race/ethnicity, baseline outcome values, and site. Analyses were conducted in 2015-2016.

Results: A total of 387 participants enrolled (273 VA-DPP, 114 MOVE!). More VA-DPP participants completed at least one (73.3% VA-DPP vs 57.5% MOVE! p=0.002); four (57.5% VA-DPP vs 42.5% MOVE!, p=0.007); and eight or more sessions (42.5% VA-DPP vs 31% MOVE!, p=0.035). Weight loss from baseline was significant at both 6 (p<0.001) and 12 months (p<0.001) for VA-DPP participants, but only significant at 6 months for MOVE! participants (p=0.004). Between groups, there were significant differences in 6-month weight loss (-4.1 kg VA-DPP vs -1.9 kg MOVE!, p<0.001), but not 12-month weight loss (-3.4 kg VA-DPP vs -2.0 kg MOVE!, p=0.16). There were no significant differences in HbA1c change or outpatient, inpatient, and total VA expenditures.

Conclusions: VA-DPP participants had higher participation rates and weight loss at 6 months, but similar weight, HbA1c, and health expenditures at 12 months compared to MOVE!

Participants: Features of VA-DPP may help enhance the capability of MOVE! to reach a larger proportion of the served population and promote individual-level weight maintenance.

Figures

Figure 1.
Figure 1.
CONSORT flow diagram of participant flow through the study. aDiabetes was defined by HbA1c>6.4% or FPG>125 mg/dL, diabetes medications or diagnosis. VA-DPP, VA Diabetes Prevention Program; BL, baseline; ITT, intent to treat; FPG, fasting blood glucose; HbA1c, Hemoglobin A1c
Figure 2.
Figure 2.
Proportion of participants who attended each session by intervention arm (N=386). Notes: Figure 2 provides a visual comparison of the percent of participants in each arm who attended cumulative sessions. For example, 73% of VA-DPP participants attended 1 or more sessions compared to 57.5% of MOVE participants (p=0.002). VA-DPP includes 16 core weekly sessions followed by biweekly sessions in first 6 months, as well as 6 monthly maintenance sessions in second 6 months. MOVE! typically includes 8–12 core weekly sessions followed by monthly maintenance sessions. VA-DPP, Veterans Affairs Diabetes Prevention Program; MOVE!, national weight loss program in the VA

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