Persistent Infections with Diverse Co-Circulating Astroviruses in Pediatric Oncology Patients, Memphis, Tennessee, USA

Emerg Infect Dis. 2017 Feb;23(2):288-290. doi: 10.3201/eid2302.161436.

Abstract

Human astroviruses are a major cause of pediatric gastroenteritis, especially in immunocompromised children. We conducted a retrospective study to demonstrate that diverse astrovirus genotypes can co-circulate in pediatric oncology patients. A subset of cases is associated with long-term virus shedding (range 17-183 days).

Keywords: HAstV; Tennessee; United States; astrovirus; cancer; children; co-circulation; enteric infections; gastroenteritis; genotype; human astroviruses; immunocompromised host; oncology; pediatric; prevalence; virus shedding; viruses.

MeSH terms

  • Adolescent
  • Age Factors
  • Astroviridae Infections / complications*
  • Astroviridae Infections / epidemiology*
  • Astroviridae Infections / virology
  • Child
  • Child, Preschool
  • Feces / virology
  • Female
  • Genotype
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Mamastrovirus* / classification
  • Mamastrovirus* / genetics
  • Neoplasms / complications*
  • Neoplasms / epidemiology*
  • Phylogeny
  • Retrospective Studies
  • Tennessee / epidemiology
  • Virus Shedding