Biofilm-Forming Capability of Highly Virulent, Multidrug-Resistant Candida auris

Emerg Infect Dis. 2017 Feb;23(2):328-331. doi: 10.3201/eid2302.161320.

Abstract

The emerging multidrug-resistant yeast pathogen Candida auris has attracted considerable attention as a source of healthcare-associated infections. We report that this highly virulent yeast has the capacity to form antifungal resistant biofilms sensitive to the disinfectant chlorhexidine in vitro.

Keywords: Candida auris; aggregative phenotypes; antifungal drug­ resistant; biofilm; candidemia; chlorhexidine; fungi; healthcare–associated infections; killing assay; multidrug resistant; nonaggregative phenotypes; virulent; yeast.

MeSH terms

  • Animals
  • Antifungal Agents / pharmacology*
  • Biofilms / growth & development*
  • Candida / drug effects*
  • Candida / pathogenicity*
  • Candidiasis / microbiology*
  • Drug Resistance, Multiple, Fungal*
  • Larva / microbiology
  • Microbial Sensitivity Tests
  • Moths / microbiology
  • Virulence

Substances

  • Antifungal Agents