Psilocybin is a naturally occurring alkaloid, pharmacologically similar to the classic hallucinogen lysergic acid diethylamide (LSD). Although primarily used as a recreational drug or an entheogen in particular cultural settings, recent population based studies have shown that it does not lead to serious physical or mental health problems or dependent use. In view of recent work demonstrating psilocybin's potential to increase subjective sense of wellbeing and because of its novel mechanism of 5-HT2A serotonin receptor agonism, it is being explored for possible therapeutic utility in mood and anxiety disorders.
Keywords: depression; hallucinogen; psilocybin; treatment.
Conflict of interest statement
The authors declare that there is no conflict of interest.
Clinical Potential of Psilocybin as a Treatment for Mental Health ConditionsJ Daniel et al. Ment Health Clin 7 (1), 24-28. PMID 29955494.Psilocybin, a classic hallucinogen, is a chemical produced by more than 100 species of mushrooms worldwide. It has high affinity for several serotonin receptors, includin …
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