Preparation and execution of teeth clenching and foot muscle contraction influence on corticospinal hand-muscle excitability

Sci Rep. 2017 Jan 24;7:41249. doi: 10.1038/srep41249.

Abstract

Contraction of a muscle modulates not only the corticospinal excitability (CSE) of the contracting muscle but also that of different muscles. We investigated to what extent the CSE of a hand muscle is modulated during preparation and execution of teeth clenching and ipsilateral foot dorsiflexion either separately or in combination. Hand-muscle CSE was estimated based on motor evoked potentials (MEPs) elicited by transcranial magnetic stimulation (TMS) and recorded from the first dorsal interosseous (FDI) muscle. We found higher excitability during both preparation and execution of all the motor tasks than during mere observation of a fixation cross. As expected, the excitability was greater during the execution phase than the preparation one. Furthermore, both execution and preparation of combined motor tasks led to higher excitability than individual tasks. These results extend our current understanding of the neural interactions underlying simultaneous contraction of muscles in different body parts.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Evoked Potentials, Motor / physiology
  • Female
  • Foot / physiology*
  • Hand / physiology*
  • Humans
  • Male
  • Muscle Contraction / physiology*
  • Muscle, Skeletal / physiology*
  • Pyramidal Tracts / physiology*
  • Tooth / physiology*
  • Young Adult